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性 別:

最高學(xué)歷、學(xué)位:博士/博士

職 稱(chēng):教授/博導(dǎo)

院內(nèi)職務(wù):傳染病診治國(guó)家重點(diǎn)實(shí)驗(yàn)室感染免疫方向負(fù)責(zé)人

個(gè)人簡(jiǎn)介

浙江大學(xué)求實(shí)特聘教授。曾受基金委杰出青年項(xiàng)目、中科院百人計(jì)劃海外人才項(xiàng)目等資助。

專(zhuān)業(yè)擅長(zhǎng)

擅長(zhǎng)急慢性病毒感染相關(guān)的免疫病理機(jī)制研究,,運(yùn)用單細(xì)胞轉(zhuǎn)錄組,、空間表達(dá)組,、單顆粒成像等現(xiàn)代技術(shù),在分子,、細(xì)胞和活體不同層面研究炎性反應(yīng)失衡的新機(jī)制和新規(guī)律。

研究方向

巨噬細(xì)胞等天然免疫識(shí)別與應(yīng)答機(jī)制,,天然免疫炎性反應(yīng)與調(diào)節(jié)等

成果獎(jiǎng)項(xiàng):(近五年主要成果及獎(jiǎng)勵(lì)情況)

近五年代表性論文:

1)         X Lin, T Twelkmeyer, D Zhu, L Zhang, Y Zhao, C Zhang, Y Iwakura, G Meng, Z Hua, B Yan, W Liu, Z Luo, S Gong, H Chen, S Li, B Hou, H Tang (2021) Homeostatic regulation of T follicular helper and antibody response to particle antigens by IL-1Ra of medullary sinus macrophage origin. Proc Natl Acad Sci USA, 118(17):e2019798118 (IF 12.777)

2)         W Zhang,Y Xu, F Zhao, M Tarbe, S Zhou, W Wang, S Zhang, W Zhang, Q Xu, L Shi, F Yuan, X Lin,S Liu, J Sun, J Zhao, Y Yang, X Liang, J Zhong, G Long, C Qin, Q Leng and H Tang (2020) The pre-existing cellular immunity to Japanese encephalitis virus heterotypically protects mice from Zika virus infection. Science Bulletin, 65(5):402-409. (IF 20.577)

3)         Zhang, C., Wang, F., Silvestre, J., Arenzana-Seisdedos F. & Tang H. (2020) Is aberrant CD8+ T cell activation by hypertension associated with cardiac injury in severe cases of COVID-19?. Cell Mol Immunol., https://doi.org/10.1038/s41423-020-0454-3 (IF 22.096)

4)         Yang S, Zhao Y, Yu J, Fan Z, Gong ST, Tang H*, Pan L*. (2019) Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila. Cell Host & Microbe. 14;26(2):240-251.e8. (IF 31.316)

5)         S Hong, Z Zhang, H Liu, M Tian, X Zhu, Z Zhang, W Wang, X Zhou, F Zhang, Q Ge, B Zhu, H Tang*, Z Hua* and B Hou* (2018) B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen. Immunity, 49:695-708. (*co-correspondence) (IF 43.474)

6)         Brey PT, Fontenille D, Tang H (2018) Yellow fever risk in Asia-Pacific region. Nature, 554:31 (IF 49.962)

7)         X He, J Yu, M Wang, Y Cheng, Y Han, S Yang, G Shi, L Sun, Y Fang, S Gong, Z Wang, YX Fu, L Pan and H Tang (2017) Bap180/Baf180 is required to maintain homeostasis of intestinal innate immune response in Drosophila and mice. Nature Microbiol, 2:17056 (IF 30.964)

 

近三年曾獲獎(jiǎng)勵(lì):

 

l  上海市“領(lǐng)軍人才”

l  全國(guó)科技系統(tǒng)抗擊新冠肺炎疫情先進(jìn)個(gè)人


社會(huì)任職

現(xiàn)兼任中國(guó)細(xì)胞生物學(xué)會(huì)常務(wù)理事,,中國(guó)免疫學(xué)會(huì)感染免疫專(zhuān)業(yè)分會(huì)副主任委員,Cellular & Molecular ImmnologyProtein & Cell編委,。