何沁
查看科室更多醫(yī)生科 室：眼科
性 別：女
最高學(xué)歷,、學(xué)位：博士,、博士
職 稱：副主任醫(yī)師
出診信息
注：出診時(shí)間如有變化，以當(dāng)日掛號(hào)為準(zhǔn)| 門診時(shí)間 | 門診地點(diǎn) |
|---|---|
| 星期 六 (上午) | 慶春院區(qū) |
| 星期 六 (下午) | 慶春院區(qū) |
個(gè)人簡介
副主任醫(yī)師,，浙江大學(xué)眼科學(xué)博士,。浙大一院2023年度醫(yī)學(xué)院級(jí)先進(jìn)工作者。從事眼科臨床工作數(shù)年,，擅長各類白內(nèi)障的診斷與手術(shù)治療,，在眼科常見病如眼底病、屈光不正,、青光眼方面積累了較豐富的經(jīng)驗(yàn),。主持多項(xiàng)國家級(jí)和省部級(jí)科研項(xiàng)目；發(fā)表SCI論著10余篇,。專業(yè)擅長
各類白內(nèi)障的診斷與手術(shù)治療,，眼科常見病如眼底病、屈光不正,、青光眼的診治,。研究方向
白內(nèi)障的臨床及基礎(chǔ)研究；細(xì)胞自噬參與眼部纖維化的基礎(chǔ)研究,。成果獎(jiǎng)項(xiàng)：（近五年主要成果及獎(jiǎng)勵(lì)情況）
(1)He Q, Cai Y, Huang J, He X, Han W, Chen W. Impairment of autophagy promotes human conjunctival fibrosis and pterygium occurrence via enhancing the SQSTM1-NF-κB signaling pathway. J Mol Cell Biol. 2023 Jun 1;15(1):mjad009. (2)He Q, Huang J, He X, Yu W, Yap M, Han W. Effect of corneal incision features on anterior and posterior corneal astigmatism and higher-order aberrations after cataract surgery. Acta Ophthalmol. 2021 Nov;99(7):e1027-e1040. (3)He Q, Huang J, Xu Y, Han W. Changes in total, anterior, and posterior corneal surface higher-order aberrations after 1.8 mm incision and 2.8 mm incision cataract surgery. J Cataract Refract Surg. 2019 Aug;45(8):1135-1147. (4)Huang J, Yu W, He Q, He X, Yang M, Chen W, Han W. Autophagy facilitates age-related cell apoptosis-a new insight from senile cataract. Cell Death Dis. 2022 Jan 10;13(1):37. (5)He X, He Q, Yuan M, Fang Z, Zhang K, Zhu T, Han W. Evaluation of morphological features: femtosecond-LASIK flap vs. SMILE cap, and the effects on corneal higher-order aberrations. Graefes Arch Clin Exp Ophthalmol. 2022 Dec;260(12):3993-4003. (6)He X, He Q, Yu W, Huang J, Yang M, Chen W, Han W. Optimized protocol for high-titer lentivirus production and transduction of primary fibroblasts. J Basic Microbiol. 2021 May;61(5):430-442. (7)Wang J, He X, He Q, Han J, Yang Z, Wang X, Han W. Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation. Front Med (Lausanne). 2024 Nov 6;11:1491901. (8)Jiang B, Hong N, Zhang L, Xu B, He Q, Qian X, Li F, Dong F. MiR-181a-5p may regulate cell proliferation and autophagy in myopia and the associated retinopathy. Exp Eye Res. 2024 Apr;241:109829. (9)Lu L, Ren P, Tang X, Yang M, Yuan M, Yu W, Huang J, Zhou E, Lu L, He Q, Zhu M, Ke G, Han W. AI-Model for Identifying Pathologic Myopia Based on Deep Learning Algorithms of Myopic Maculopathy Classification and "Plus" Lesion Detection in Fundus Images. Front Cell Dev Biol. 2021 Oct 15;9:719262. (10)Lu L, Zhou E, Yu W, Chen B, Ren P, Lu Q, Qin D, Lu L, He Q, Tang X, Zhu M, Wang L, Han W. Development of deep learning-based detecting systems for pathologic myopia using retinal fundus images. Commun Biol. 2021 Oct 26;4(1):1225. (11)Shen Y, Shen H, Guo D, Sun X, Sun Y, Hong N, Wang X, Xie C, Zhao Y, He Q, Jin L, Wen Y, Jiang B, Yu C, Zhu M, Cai F, Dai J. Recent developments in regenerative ophthalmology. Sci China Life Sci. 2020 Oct;63(10):1450-1490. (12)小梁網(wǎng)細(xì)胞線粒體自噬缺陷通過mtDNA/cGAS/STING 通路調(diào)節(jié)衰老相關(guān)分泌表型（SASP）加重小梁網(wǎng)纖維化的機(jī)制研究, 國家自然科學(xué)基金委, 在研, 主持 (13)成纖維細(xì)胞自噬缺陷促進(jìn)胬肉形成以及雷帕霉素干預(yù)治療的機(jī)制研究, 浙江省自然科學(xué)基金委, 結(jié)題, 主持 (14)自噬調(diào)控p62-Keap1-Nrf2 信號(hào)通路參與年齡相關(guān)性白內(nèi)障發(fā)病的作用及機(jī)制研究, 中國博士后科學(xué)基金, 結(jié)題, 主持 (15)浙大一院2023年度醫(yī)學(xué)院級(jí)先進(jìn)工作者
