黃金艷
查看科室更多醫(yī)生性 別：男
最高學(xué)歷、學(xué)位：博士研究生；博士
職 稱：研究員
院內(nèi)職務(wù)：主任
個(gè)人簡(jiǎn)介
浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院生物醫(yī)學(xué)大數(shù)據(jù)中心負(fù)責(zé)人。2009年，赴法國(guó)巴黎國(guó)家測(cè)序中心和人類多態(tài)性研究中心(CEPH)從事高通量數(shù)據(jù)分析研究工作。2011年-2014年，于哈佛大學(xué)公共衛(wèi)生學(xué)院從事博士后研究工作,。2014年回國(guó)，受聘于上海交通大學(xué)醫(yī)學(xué)院附屬瑞金醫(yī)院血研所,。擔(dān)任中國(guó)醫(yī)藥生物技術(shù)協(xié)會(huì)基因檢測(cè)技術(shù)分會(huì)委員,、中國(guó)病理生理學(xué)會(huì)實(shí)驗(yàn)血液學(xué)青年委員會(huì)委員和中-法應(yīng)用科學(xué)會(huì)(FFCSA)俱樂部主席。研發(fā)了一系列醫(yī)療衛(wèi)生軟件系統(tǒng),，在《Cancer Cell》,、《Genome Biology》、《PNAS》和《Bioinformatics》等學(xué)術(shù)刊物以第一或通訊作者發(fā)表SCI論文50余篇,，總影響因子超過500,，共同主編了《R語言在生物醫(yī)學(xué)領(lǐng)域的應(yīng)用》一書。取得軟件著作權(quán)2項(xiàng),，申請(qǐng)專利6項(xiàng),。
專業(yè)擅長(zhǎng)
擅長(zhǎng)高通量數(shù)據(jù)分析研究，以及生物醫(yī)學(xué)大數(shù)據(jù)整合與挖掘,。
研究方向
組學(xué)數(shù)據(jù)的分析與挖掘,，惡性腫瘤分子分型和發(fā)病機(jī)制研究。
成果獎(jiǎng)項(xiàng)：（近五年主要成果及獎(jiǎng)勵(lì)情況）
一,、成果
（一）發(fā)表文章
2021年
1. Sangyoon Yi, Xianyang Zhang, Lu Yang, Jinyan Huang, Yuanhang Liu, Chen Wang, Daniel J. Schaid, Jun Chen, 2dFDR: a new approach to confounder adjustment substantially increases detection power in omics association studies, Genome Biology, July 13. doi: https://doi.org/10.1186/s13059-021-02418-8. (期刊影響因子：14.2)
2. Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang, Clinical significance of CD34 + CD117 dim/CD34 + CD117 bri myeloblast-associated gene expression in t(8;21) acute myeloid leukemia, Frontiers of Medicine, Mar 23. doi: 10.1007/s11684-021-0836-7. (期刊影響因子：3.42)
3. Hao Tang, Yijun Cheng, Jinyan Huang, Jianfeng Li, Benyan Zhang, Zhe Bao Wu, Case Report: Temozolomide Treatment of Refractory Prolactinoma Resistant to Dopamine Agonists, Front Endocrinol. 2021 Mar 12;12:616339. doi: 10.3389/fendo.2021.616339. (期刊影響因子：3.675)
4. Liang Wu, Minghao Jiang, Ping Yu, Jianfeng Li, Wen Ouyang, Chong Feng, Wei Li Zhao, Yuting Dai and Jinyan Huang*, Single-Cell Transcriptome Analysis Identifies Ligand–Receptor Pairs Associated With BCP-ALL Prognosis, Frontiers in Oncology, 2021 Mar 10;11:639013. doi: 10.3389/fonc.2021.639013. eCollection 2021 (通訊作者,，期刊影響因子：4.848)
5. Yuting Dai, Aining Xu, Jianfeng Li, Liang Wu, Shanhe Yu, Jun Chen, Weili Zhao, Xiao-Jian Sun and Jinyan Huang*, CytoTree: an R/Bioconductor package for analysis and visualization of flow and mass cytometry data, BMC Bioinformatics, 2021 Mar 22;22(1):138. doi: 10.1186/s12859-021-04054-2. (通訊作者，期刊影響因子：3.242)
6. Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Jinyan Huang* and Sai-Juan Chen*, Emerging Molecular Subtypes and Therapeutic Targets in B-cell Precursor Acute Lymphoblastic Leukemia, Frontiers of Medicine, 2021 Jan 5. doi: 10.1007/s11684-020-0821-6. (共同通訊作者,，期刊影響因子：3.42)
2020年
7. Yaohui huang, Kun Cai, PengPeng Xu, Li Wang, ChuanXin Huang, Ying Fang, Shu Cheng, Xiao-Jian Sun, Feng Liu, Jinyan Huang, and MengMeng Ji, Wei-Li Zhao, CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis, Signal Transduction and Targeted Therapy, 2020 Nov;10(7):e221.doi: 10.1002/ctm2.221. (期刊影響因子：13.49)
8. Rong Shen, Peng-Peng Xu, Nan Wang, Hong-Mei Yi, Lei Dong, Di Fu, Jinyan Huang, Heng-Ye Huang, Anne Janin, Shu Cheng, Li Wang, Wei-Li Zhao, Influence of oncogenic mutations and tumor microenvironment alterations on extranodal invasion in diffuse large B-cell lymphoma, Clinical and Translational Medicine, 2020 Nov;10(7):e221.doi: 10.1002/ctm2.221. (期刊影響因子：7.92)
9. Lu Jiang, Xue-Ping Li, Yu-Ting Dai, Jinyan Huang*, Zhu Chen* and Sai-Juan Chen*, Multidimensional Study of the Heterogeneity of Leukemia Cells in t(8;21) AML Identifies the Subtype with Poor Outcome, PNAS, 2020 Aug 18;117(33):20117-20126. doi: 10.1073/pnas.2003900117. (共同通訊作者,，期刊影響因子：9.58)
10. Mingjie Wang, Jianfeng Li, Xiaonan Zhang, Yue Han, Demin Yu, Donghua Zhang, Zhenghong Yuan, Zhitao Yang, Jinyan Huang* and Xinxin Zhang*, An integrated software for virus community sequencing data analysis, BMC Genomics, 2020 May 15;21(1):363. doi: 10.1186/s12864-020-6744-4. (共同通訊作者，期刊影響因子：3.68)
11. Li SX, Chen XJ, Jiang L, Lei YC, Zhang YX, Dai B, Zhang WN, Zhong ML, Fan YL, Chen QS, Liu H, Jinyan Huang, Chen B, Identification of a t(X;17)(q28;q21) generating a KANSL1-MTCP1 gene fusion leading to dysregulated expression of MTCP1 in acute myeloid leukemia, Genes Chromosomes Cancer, 2020 Jul;59(7):417-421. doi: 10.1002/gcc.22840. (期刊影響因子：3.56)
12. Chang R, Wang H, Zhang S, Wang Z, Dong Y, Tsamlag L, Yu X, Xu C, Yu Y, Long R, Liu NN, Chu Q, Wang Y, Xu G, Shen T, Wang S, Deng X, Jinyan Huang, Zhang X, Wang H, Cai Y. Phase- and epidemic region-adjusted estimation of the number of coronavirus disease 2019 cases in China. Frontiers of Medicine, 2020 Apr;14(2):199-209. doi: 10.1007/s11684-020-0768-7. (期刊影響因子：3.54)
13. Kai Duan, Bende Liu, Cesheng Li, Huajun Zhang, Ting Yu, Jieming Qu, Min Zhou, Li Chen, Shengli Meng, Yong Hu, Cheng Peng, Mingchao Yuan, Jinyan Huang, Zejun Wang, Jianhong Yu, Xiaoxiao Gao, Dan Wang, Xiaoqi Yu, Li Li, Jiayou Zhang, Xiao Wu, Bei Li, Yanping Xu, Wei Chen, Yan Peng, Yeqin Hu, Lianzhen Lin, Xuefei Liu, Shihe Huang, Zhijun Zhou, Lianghao Zhang, Yue Wang, Zhi Zhang, Kun Deng, Zhiwu Xia, Qin Gong, Wei Zhang, Xiaobei Zheng, Ying Liu, Huichuan Yang, Dongbo Zhou, Ding Yu, Jifeng Hou, Zhengli Shi, Saijuan Chen, Zhu Chen*, Xinxin Zhang*, and Xiaoming Yang*, Effectiveness of convalescent plasma therapy in severe COVID-19 patients, PNAS. 2020 Apr 28;117(17):9490-9496. doi: 10.1073/pnas.2004168117. (期刊影響因子：9.58)
14. Jinyan Huang*, Ling Bai, Bowen Cui, Liang Wu, Liwen Wang, Zhiyin An, Shulin Ruan, Yue Yu, Xianyang Zhang, Jun Chen, Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing, Genome Biology, 2020 Apr 6;21(1):88. doi: 10.1186/s13059-020-02001-7. (第一作者,、通訊作者,，期刊影響因子：14.03)
15. Jie Xiong#, Bo-Wen Cui#, Nan Wang#, Yu-Ting Dai#, Hao Zhang#, Chao-Fu Wang#, Hui-Juan Zhong, Shu Cheng, Bin-Shen Ou-Yang, Yu Hu, Xi Zhang, Bin Xu, Wen-Bin Qian, Rong Tao, Feng Yan, Jian-Da Hu, Ming Hou, Xue-Jun Ma, Xin Wang, Yuan-Hua Liu, Zun-Min Zhu, Xiao-Bin Huang, Li Liu, Chong-Yang Wu, Li Huang, Yun-Feng Shen, Rui-Bin Huang, Jing-Yan Xu, Chun Wang, De-Pei Wu, Li Yu, Jian-Feng Li, Peng-Peng Xu, Li Wang, Jinyan Huang*, Sai-Juan Chen*, and Wei-Li Zhao*, Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma, Cancer Cell, 2020 Mar 16;37(3):403-419.e6. doi: 10.1016/j.ccell.2020.02.005. (共同通訊作者，期刊影響因子：26.6)
16. Huwen Wang, Zezhou Wang, Yinqiao Dong, Ruijie Chang, Chen Xu, Xiaoyue Yu, Shuxian Zhang, Lhakpa Tsamlag, Meili Shang, Jinyan Huang, Ying Wang, Gang Xu, Tian Shen, Xinxin Zhang, Yong Cai, Phase-adjusted estimation of the number of Coronavirus Disease 2019 cases in Wuhan, China, Cell Discovery, 2020 Feb 24;6:10. doi: 10.1038/s41421-020-0148-0. (期刊影響因子：4.6)
2019年
17. Yi Zhou, Xingli Zhu, Yuting Dai, Shumin Xiong, Chuijin Wei, Pei Yu, Yuewen Tang, Liang Wu, Jianfeng Li, Dan Liu, Yanlin Wang, Zhu Chen, Sai-Juan Chen*, Jinyan Huang*, and Lin Cheng*, Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells. Advanced Science. 2019 Nov 11;7(1):1901785. doi: 10.1002/advs.201901785. eCollection 2020 Jan. (共同通訊作者，期刊影響因子：15.8)
18. Chen-Lei Wen, et.al., Jinyan HUANG, et.al., Sai-Juan Chen, Zhu Chen*, Min Lik*, Yuan Fang*, Bai-Yong Shen*, and Lu Zhou*, An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma. PNAS. 2019 Nov 12;116(46):23264-23273. doi: 10.1073/pnas.1914557116. Epub 2019 Oct 29. (期刊影響因子：9.58)
19. Yao H, Tang H, Zhang Y, Zhang QF, Liu XY, Liu YT, Gu WT, Zheng YZ, Shang HB, Wang Y, Jinyan HUANG, Wei YX, Zhang X, Zhang J, Wu ZB, DEPTOR inhibits cell proliferation and confers sensitivity to dopamine agonist in pituitary adenoma, Cancer Lett. 2019 Sep 10;459:135-144. doi: 10.1016/j.canlet.2019.05.043. Epub 2019 Jun 6. (期刊影響因子：6.5)
20. Merino J, Dashti HS, et.al., Jinyan Huang, et.al., Chu AY, Tanaka T, Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry. 2019 Dec;24(12):1920-1932. doi: 10.1038/s41380-018-0079-4. Epub 2018 Jul 9. (期刊影響因子：12)
21. Clark DW, Okada Y, Moore KHS, et.al., Jinyan Huang, et.al., Joshi PK, Kubo M, Wilson JF, Associations of autozygosity with a broad range of human phenotypes, Nature Communication. 2019 Oct 31;10(1):4957. doi: 10.1038/s41467-019-12283-6. (期刊影響因子：11.9)
22. Wang D, Zhang G, Gu J, Shao X, Dai Y, Li J, Pan X, Yao S, Xu A, Jin Y, Jinyan Huang, Shi Q, Zhu J, Xi X, Chen Z, Chen S., In vivo generated hematopoietic stem cells from genome edited induced pluripotent stem cells are functional in platelet-targeted gene therapy of murine hemophilia A. Haematologica. 2019 Jul 11. pii: haematol.2019.219089. doi: 10.3324/haematol.2019.219089. (期刊影響因子：7.57)
2018年
23. Jianfeng Li#,Yu-Ting Daia, Henrik Lilljebj?rnb, Shu-Hong Shen, Bo-Wen Cui, Ling Bai, Yuan-Fang Liu, Mao-Xiang Qian, Yasuo Kubota, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki, Linda Olsson, Ah Moy Tan, Hany Ariffin, Jing Chen, Junko Takita, Takahiko Yasuda, Hiroyuki Mano, Bertil Johansson, Jun J. Yang, Allen Eng-Juh Yeoh, Fumihiko Hayakawa, Zhu Chen*, Ching-Hon Pui*, Thoas Fioretos*, Sai-Juan Chen*, Jinyan Huang*, Transcriptional landscape of B-cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases. PNAS. 2018 Dec 11;115(50):E11711-E11720. doi: 10.1073/pnas.1814397115. Epub 2018 Nov 28. (通訊作者,，期刊影響因子：9.58)
24. Jianfeng Li#,et.,al, Jinyan Huang*, BioInstaller: a comprehensive R package to construct interactive and reproducible biological data analysis applications based on the R platform. Peerj. 2018 Oct 31; 6:e5853. (通訊作者，期刊影響因子：2.353)
25. Huizhuang Shan, et.,al, Jinyan Huang, et.,al, Yingli Wu, USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia. Signal Transduction and Targeted Therapy. 2018 Oct 26;3:29. doi: 10.1038/s41392-018-0028-3. eCollection 2018. (期刊影響因子：5.873)
26. Dong X#, Zhang W#, Wu H#, Jinyan Huang#, Zhang M, Wang P, Zhang H, Chen Z, Chen SJ, Meng G, Structural basis of DUX4/IGH-driven transactivation. Leukemia. 2018 Jun;32(6):1466-1476. (共同第一,，期刊影響因子：9.944)
27. Meng-Meng Ji#, Yao-Hui Huang#, Jinyan Huang#, Zhao-Fu Wang, Di Fu, Han Liu, Feng Liu, Christophe Leboeuf, Li Wang, Jing Ye, Yi-Ming Lu, Anne Janin, Shu Cheng and Wei-Li Zhao, Histone modifier gene mutations in peripheral T-cell lymphoma not otherwise specified. Haematologica. 2018 Apr;103(4):679-687. (共同第一,，期刊影響因子：7.570)
28. Merino J, Dashti HS, et.al., Jinyan HUANG, et.al., Chu AY, Tanaka T., Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Mol Psychiatry. 2019 Dec;24(12):1920-1932. (期刊影響因子：11.973)
29. Wang S, Zhang YX, Huang T, Sui JN, Lu J, Chen XJ, Wang KK, Xi XD, Li JM, Jinyan Huang*, Chen Bin*, Mutation profile and associated clinical features in Chinese patients with cytogenetically normal acute myeloid leukemia. Int J Lab Hematol. 2018 Aug;40(4):408-418. (共同通訊作者，期刊影響因子：2.073)
2017年
30. Bing Chen, Lu Jiang, Meng-Ling Zhong, Jian-Feng Li, Ben-Shang Li, Li-Jun Peng, Yu-Ting Dai, Bo-Wen Cui, Tian-Qi Yan, Wei-Na Zhang, Xiang-Qin Weng, Yin-Yin Xie, Jing Lu, Rui-Bao Ren, Su-Ning Chen, Jian-Da Hu, De-Pei Wu, Zhu Chen*, Jing-Yan Tang*, Jinyan Huang*, Jian-Qing Mi*, Sai-Juan Chen*, Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. PNAS. 2018 Jan 9;115(2):373-378. (共同通訊作者,，期刊影響因子：9.58)
31. Jun Chen, Ehsan Behnam, Jinyan Huang, Miriam F. Moffatt, Daniel J. Schaid, Liming Liang and Xihong Lin, Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA. BMC Genomics. 2017 May 26;18(1):413. (期刊影響因子：3.501)
32. Yu-Jun Dai#, Yue-Ying Wang#, Jinyan Huang#, Li Xia, Xiao-Dong Shi, Jie Xu, Jing Lu, Xian-Bin Su, Ying Yang, Wei-Na Zhang, Pan-Pan Wang, Song-Fang Wu, Ting Huang, Jian-Qing Mi, Ze-Guang Han, Zhu Chen, and Sai-Juan Chen, Conditional knock-in of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement. PNAS. 2017 May 16;114(20):5237-5242. (共同第一,，期刊影響因子：9.58)
33. Yong?Mei Zhu, Pan?Pan Wang, Jinyan Huang, et.al., Sai-Juan Chen and Yang Shen, Gene mutational pattern and expression level in 560 acute myeloid leukemia patients and their clinical relevance. Journal of Translational Medicine. 2017 Aug 22;15(1):178. (期刊影響因子：4.098)
34. Mingjie WANG, et al., Jinyan Huang*, Xinxin ZHANG*, Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis. Scientific Reports. 2017 Mar 6;7:43446. (共同通訊作者，期刊影響因子：4.011)
35. Omer Schwartzman, Angela Maria Savino, Michael Gombert, Chiara Palmi, Gunnar Cario, Martin Schrappe, Cornelia Eckert, Arend von Stackelberg, Jinyan Huang, Michal Hameiri-Grossman, Smadar Avigad, Geertruy te Kronnie, Ifat Geron, Yehudit Birger, Avigail Rein, Giulia Zarfati, Ute Fischer, Zohar Mukamel, Martin Stanulla, Andrea Biondi, Giovanni Cazzaniga, Amedeo Vetere, Bridget K. Wagner, Zhu Chen, Sai-Juan Chen, Amos Tanay, Arndt Borkhardt, and Shai Izraeli, Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome. PNAS. 2017 May 16;114(20):E4030-E4039. (期刊影響因子：9.58)
36. Peng-Peng Xu, Hui-Juan Zhong, Yao-Hui Huang, Xiao-Dong Gao, Xia Zhao, Yang Shen, Shu Cheng, Jinyan Huang, Sai-Juan Chen, Li Wang, Wei-Li Zhao, B-cell Function Gene Mutations in Diffuse Large B-cell Lymphoma: A Retrospective Cohort Study. Ebiomedicine. 2017 Feb;16:106-114. (期刊影響因子：6.680)
37. Peng-Peng Xu, Hui-Juan Zhong, Yao-Hui Huang, Xiao-Dong Gao, Xia Zhao, Yang Shen, Shu Cheng, Jinyan Huang, Sai-Juan Chen, Li Wang, Wei-Li Zhao, A low-frequency inactivating AKT2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk. Diabetes. 2017 Jul;66(7):2019-2032. (期刊影響因子：7.199)
38. Jun Li, Xiaoyan Zhu, Kuai Yu, Haijing Jiang, Yizhi Zhang, Siyun Deng, Longxian Cheng, Xuezhen Liu, Jia Zhong, Xiaomin Zhang, Mei'an He, Weihong Chen, Jing Yuan, Ming Gao, Yansen Bai, Xu Han, Bing Liu, Xiaoting Luo, Wenhua Mei, Xiaosheng He, Shunchang Sun, Liyun Zhang, Hesong Zeng, Huizhen Sun, Chuanyao Liu, Yanjun Guo, Bing Zhang, Zhihong Zhang, Jinyan Huang, An Pan, Yu Yuan, Francesca Angileri, Bingxia Ming, Fang Zheng, Qiutang Zeng, Xiaobo Mao, Yudong Peng, Yi Mao, Ping Ye, Qing K Wang, Lu Qi, Frank B Hu, Liming Liang, Tangchun Wu, Genome-Wide Analysis of DNA Methylation and Acute Coronary Syndrome. Circulation Research. 2017 May 26;120(11):1754-1767. (期刊影響因子：15.862)
39. Lindstr?m S, Loomis S, Turman C, Huang H, Jinyan Huang, Aschard H, Chan AT5, Choi H, Cornelis M, Curhan G, De Vivo I, Eliassen AH, Fuchs C, Gaziano M11, Hankinson SE, Hu F, Jensen M, Kang JH8, Kabrhel C, Liang L, Pasquale LR, Rimm E, Stampfer MJ, Tamimi RM, Tworoger SS, Wiggs JL, Hunter DJ, Kraft P, A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts. PloS One. 2017 Mar 16;12(3):e0173997. (期刊影響因子：2.776)
2016年
40. Li Man, et al., Jinyan Huang, et al., SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar;28(3):981-994. (期刊影響因子：8.547)
41. Pan M, et al., Jinyan Huang, et al., Human NUP98-IQCG fusion protein induces acute myelomonocytic leukemia in mice by dysregulating the Hox/Pbx3 pathway, Leukemia. 2016 Jul;30(7):1590-3. (期刊影響因子：9.944)
42. Pan M, et al., Jinyan Huang, et al., Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG. Front Med. 2016 Dec;10(4):410-419. (期刊影響因子：1.847)
43. Wu M, et al., Jinyan Huang, et al., N-Arachidonoyl Dopamine Inhibits NRAS Neoplastic Transformation by Suppressing Its Plasma Membrane Translocation. Mol Cancer Ther. 2017 Jan;16(1):57-67. (期刊影響因子：4.856)
44. Fuchsberger C, et al., Jinyan Huang, et al., The genetic architecture of type 2 diabetes. Nature. 2016 Aug 4;536(7614):41-47. (期刊影響因子：43.070)
45. Yuanfang Liu, et al., Jinyan Huang, et al., Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia. Ebiomedicine. 2016 Jun;8:173-183. (共同通訊作者,，期刊影響因子：6.680)
46. Machiela MJ, et al., Jinyan Huang, et al., Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. Human Molecular Genetics. 2016 Apr 15;25(8):1663-76. (期刊影響因子：4.544)
47. Berndt SI, et al., Jinyan Huang, et al., Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nature Communication. 2016 Mar 9;7:10933. (期刊影響因子：11.878)
48. Felix JF, et al., Jinyan Huang, et al., Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics. 2016 Jan 15;25(2):389-403. (期刊影響因子：4.544)
（二）科研項(xiàng)目
1. 題目: 基于分子分型的腦膠質(zhì)瘤和急性白血病精準(zhǔn)診斷,，SQ2019YFE010340
2020/01-2022/12，科技部國(guó)家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目,，800萬元
參與情況: 子課題負(fù)責(zé)人
2. 題目: 急性T淋巴細(xì)胞白血病的基因組及轉(zhuǎn)錄組生物信息學(xué)分析方法建立及數(shù)據(jù)分析,，82070147
2021/01-2024/12，國(guó)家自然科學(xué)基金面上項(xiàng)目,，55萬元
參與情況: 項(xiàng)目負(fù)責(zé)人
3. 題目: 急性B淋巴細(xì)胞白血病(BCP-ALL)的分子分型研究,，20161303R
2019/01-2021/12，上海市科委“臨床專職科研隊(duì)伍”雙百人項(xiàng)目,，130萬元
參與情況: 項(xiàng)目負(fù)責(zé)人
4. 題目: 急性T淋巴細(xì)胞白血病(T-ALL)的分子分型研究,，20161303
2016/01-2018/12，上海市科委“臨床專職科研隊(duì)伍”雙百人項(xiàng)目,，130萬元
參與情況: 項(xiàng)目負(fù)責(zé)人
5. 題目: 基于全基因組測(cè)序建立病毒拷貝數(shù)和整合位點(diǎn)的生物信息學(xué)方法及數(shù)據(jù)分析,，81770205
2018/01-2021/12，國(guó)家自然科學(xué)基金面上項(xiàng)目,，55萬元
參與情況: 項(xiàng)目負(fù)責(zé)人
6. 題目: 成人及兒童急性淋巴細(xì)胞白血病的基因組轉(zhuǎn)錄組生物信息學(xué)分析方法建立及數(shù)據(jù)分析, 81570122
2016/01-2019/12,，國(guó)家自然科學(xué)基金面上項(xiàng)目，60萬元
參與情況: 項(xiàng)目負(fù)責(zé)人
12月,，國(guó)家重點(diǎn)研發(fā)計(jì)劃,，320萬元
參與情況: 項(xiàng)目骨干
7. 題目: 誘導(dǎo)多能干細(xì)胞基因和信號(hào)調(diào)控網(wǎng)絡(luò)的研究, 30900838
2010/01-2012/12，國(guó)家自然科學(xué)基金青年項(xiàng)目,，20萬元
參與情況: 項(xiàng)目負(fù)責(zé)人
（三）研發(fā)專利及軟件著作權(quán)
1. 用于下載,、安裝、管理生物信息軟件,、數(shù)據(jù)庫的方法及系統(tǒng)（2018年）
2. 一種生物信息數(shù)據(jù)庫注釋方法及系統(tǒng)（2018年）
3. 基于RNA-seq數(shù)據(jù)的腫瘤基因突變檢測(cè)方法及系統(tǒng)（2018年）
4. 阿爾法醫(yī)生基因檢測(cè)系統(tǒng)（2016年）
5. 阿爾法醫(yī)生基因檢測(cè)報(bào)告系統(tǒng)（2016年）
二,、獎(jiǎng)勵(lì)
2018 首屆“轉(zhuǎn)化醫(yī)學(xué)獎(jiǎng)勵(lì)計(jì)劃”創(chuàng)新獎(jiǎng)
2018 國(guó)家科學(xué)技術(shù)進(jìn)步二等獎(jiǎng)(排名第四)。
2018 長(zhǎng)木(Long wood, Boston)學(xué)術(shù)獎(jiǎng)
2018 湘醫(yī)聯(lián)盟杰出人才獎(jiǎng)
2016 上海市教育委員會(huì)高峰高原學(xué)科人才建設(shè)計(jì)劃,，編號(hào)：20161303
2015 上海浦江人才,，編號(hào)：15PJ1405300
2015 上海高校青年東方學(xué)者，編號(hào)：QD2015005
2014 Gilles kahn Prize吉爾·卡恩科學(xué)獎(jiǎng), Sino French Foundation for Science and its Applications (FFCSA).
社會(huì)任職
1. Frontiers in Genetics雜志Guest Associate Editor（2021年）
2. 中國(guó)抗癌協(xié)會(huì)病理專業(yè)委員會(huì)腫瘤分子病理協(xié)作組委員（2019年）
3. 上海交通大學(xué)-耶魯大學(xué)生物統(tǒng)計(jì)和數(shù)據(jù)科學(xué)聯(lián)合中心研究員（2019年）
4. 中國(guó)醫(yī)藥生物技術(shù)協(xié)會(huì)基因檢測(cè)技術(shù)分會(huì)委員（2018年）
5. 法中應(yīng)用科學(xué)會(huì)(FFCSA)俱樂部主席（2018年）
6. 中國(guó)病理生理學(xué)會(huì)實(shí)驗(yàn)血液學(xué)青年委員會(huì)委員（2017年）
