
宋朋紅
查看科室更多醫(yī)生出診信息
注:出診時間如有變化,,以當日掛號為準門診時間 | 門診地點 |
---|
個人簡介
浙江大學(xué)外科學(xué)博士研究生導(dǎo)師,衛(wèi)健委多器官聯(lián)合移植研究重點實驗室PI,,世界生理協(xié)會,、歐洲生理協(xié)會會員,中華醫(yī)學(xué)會器官移植分會異種移植學(xué)組常委,。主要研究方向為腫瘤學(xué),、消化系統(tǒng)疾病發(fā)病機制的基礎(chǔ)研究以及臨床需求為導(dǎo)向的臨床應(yīng)用基礎(chǔ)研究。主持國家自然科學(xué)基金面上項目5項,、浙江省重點研發(fā)國際合作項目1項,、十三五傳染病重大專項子任務(wù)1項、省自然科學(xué)基金面上項目2項,、錢江人才計劃1項,、省創(chuàng)新團隊子課題1項、教育部留學(xué)回國基金1項,。以第一或通訊作者在Oncogene,、IJC等雜志發(fā)表論文多篇。
研究方向
研究方向為腫瘤學(xué),、消化系統(tǒng)疾病發(fā)病機制的基礎(chǔ)研究以及臨床需求為導(dǎo)向的臨床應(yīng)用基礎(chǔ)研究,。
成果獎項:(近五年主要成果及獎勵情況)
1) 國家自然科學(xué)基金面上項目“維生素D受體在膽固醇結(jié)石形成過程中的作用及機制研究”82070652 2021/01/01-2024/12/31 66萬
2) 浙江省重點研發(fā)計劃(國際合作)項目 “基于分子分型的AFP陰性肝癌臨床早期診斷與藥物治療研究”2020C04003 2020/01/01-2023/12/31 250萬
3) 國家自然科學(xué)基金面上項目“膽道梗阻導(dǎo)致腸道機械屏障損傷及其分子機制研究”81870434 2019/01/01-2022/12/31 68.4萬
4) 國家自然科學(xué)基金面上項目“膽道梗阻后腸道分泌和吸收功能的改變及其細胞分子機制研究”81570575 2016/01/01-2019/12/31 68.4萬
5) 十三五傳染病重大專項子任務(wù) “肝癌肝移植不同復(fù)發(fā)類型的早期預(yù)警” 2017ZX10203205-003-005 2017/01/01-2020/12/30 23.3萬
近五年發(fā)表的論文(通訊作者或者第一作者)
1) Chen J, Xuan Z, Song W, Han W, Chen H, Du Y, Xie H, Zhao Y, Zheng S*, Song P*. EAG1 enhances hepatocellular carcinoma proliferation by modulating SKP2 and metastasis through pseudopod formation Oncogene. 2021 Jan;40(1):163-176. doi: 10.1038/s41388-020-01522-6. Epub 2020 Oct 24
2) Zhao L, Xuan Z, Song W, Zhang S, Li Z, Song G, Zhu X, Xie H, Zheng S*, Song P*. A novel role for farnesoid X receptor in the bile acid-mediated intestinal glucose homeostasis J Cell Mol Med. 2020 Nov;24(21):12848-12861. doi: 10.1111/jcmm.15881. Epub 2020 Oct 8.
3) Li Z, Xuan Z, Chen J, Song W, Zhang S, Jin C, Zhou M, Zheng S*, Song P*, Inhibiting the NF-κB pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer. Int. J. Oncol. 2020 Jul;57(1).
4) Xuan Z#, Zhao L#, Li Z, Song W, Chen J, Chen J, Chen H, Song G, Jin C, Zhou M, Xie H, Zheng S*, Song P*. EPS8L3 promotes hepatocellular carcinoma proliferation and metastasis by modulating EGFR dimerization and internalization. Am J Cancer Res 2020; 10(1):60-77.
5) Chen J, Li Z,Chen J,Du Y, Song W, Xuan Z, Zhao L, Song G, Song P*, Zheng S*. Downregulation of MGMT Promotes Proliferation of Intrahepatic Cholangiocarcinoma by Regulating p21.Clin Transl Oncol.2020 Mar;22(3):392-400
6) Du Y, Song W, Chen J, Chen H, Xuan Z, Zhao L, Chen J, Jin C, Zhou M, Tuo B, Zhao Y, Zheng S*, Song P*. The potassium channel KCa3.1 promotes cell proliferation by activating SKP2 and metastasis through the EMT pathway in hepatocellular carcinoma. Int J Cancer 2019; 145(2):503-516.
7) Chen H, Chen J, Zhao L, Song W, Xuan Z, Chen J, Li Z, Song G, Hong L, Song P*, Zheng S*. CDCA5, Transcribed by E2F1, Promotes Oncogenesis by Enhancing Cell Proliferation and Inhibiting Apoptosis via the AKT Pathway in Hepatocellular Carcinoma. J Cancer 2019; 10(8):1846-1854.
8) Chen J, Song W, Du Y, Li Z, Xuan Z, Zhao L, Chen J, Zhao Y, Tuo B, Zheng S*, Song P*. Inhibition of KLHL21 prevents cholangiocarcinoma progression through regulating cell proliferation and motility, arresting cell cycle and reducing Erk activation. Biochem Biophys Res Commun 2018; 499(3):433-440.
9) Song P, Du Y, Song W, Chen H, Xuan Z, Zhao L, Chen J, Chen J, Guo D, Jin C, Zhao Y, Tuo B, Zheng S*. KCa3.1 as an Effective Target for Inhibition of Growth and Progression of Intrahepatic Cholangiocarcinoma. J Cancer 2017 Jun; 8(9):1568-1578.
10) Du Y, Chen H, Xuan Z, Song W, Hong L, Guo D, Li H, Tuo B, Zheng S, Song P*. Bile deficiency induces changes in intestinal glucose absorption in mice. Surgery 2016; 160(6):1496-1507.
社會任職
世界生理協(xié)會、歐洲生理協(xié)會會員,,中華醫(yī)學(xué)會器官移植分會異種移植學(xué)組常委